CSN: Are the Phillies spending money wisely?

Sports Illustrated recently released its ?Fortunate 50." Four Phillies are very fortunate indeed -- which, as it turns out, isn?t quite the same thing as the Phillies being fortunate.

The rankings factor in salary as well as endorsements. There weren?t any Eagles on the list. Or Sixers. Or Flyers. Cliff Lee came in 17th. He?ll make $25.28 million this year. Ryan Howard was 25th. He?ll earn $23.2 million. Roy Halladay was 39th. He?ll collect $20.21 million. And Cole Hamels was 44th. He?ll pocket $19.9 million.

Again, those totals include income from outside concerns, but not as much as you might think. According to baseballreference.com, $25 million of Lee?s money comes courtesy of the Phillies. Howard gets $20 million from the club. Halladay gets another $20 million from the Phillies. And Hamels gets $19.5 million.

The math experts among you no doubt added up the total and concluded that those four players will cost the Phillies $84.5 million this season. That?s more than the Mariners, Twins, Brewers, Royals, Rockies, Indians, Pirates, Padres, Rays, A?s, Marlins and Astros budgeted as of Opening Day, according to Yahoo! Sports.

The Phils had a total opening day payroll of $158 million. Only the Los Angeles Dodgers ($214 million) and New York Yankees ($211 million) had bigger budgets.

The Phillies, as we know, are spenders. But are they getting a solid return on their investment?

The Indians beat the Phillies, 10-4, at Citizens Bank Park on Wednesday (see story).?The Fightins are 19-22. Not terrible. Not great. After Wednesday's loss, they were four games behind first-place Atlanta (which also had a day game). Again, not terrible. But not great, either.

No. 44 on the Fortunate 50 list took the mound for the Phillies on Wednesday. Hamels threw five innings, allowing six hits, five earned runs, two walks and two homers. He also struck out four. He got the loss again, dropping his record to 1-6 this season. There have been quite a few games this season in which Hamels didn?t get adequate run support and the loss really wasn?t his fault. Wednesday wasn?t one of those days. He simply didn?t pitch that well.

?You wake up and get ready for the game and you know you?re facing a tough team and you have to go out there and execute pitches, and I wasn?t able to do that early on,? Hamels said. ?Anytime you go 3-2 [pitch count] to pretty much the whole lineup, over and over, you?re not putting yourself in a good spot.

"Pitching myself into situations where, most likely, they?re going to get hits, they?re going to get walks, they?re going to score the runs. That doesn?t keep my team, obviously, on their toes and ready for the ball if it is hit to them. It just makes for a really boring game. And, obviously, a losing game because that was the effort it entailed. That?s the really unfortunate part of how it went [Wednesday]. I?ve got a lot of work to do.?

Despite the unsightly record (again, not his fault for the most part), Hamels has been OK this year (though his 4.61 ERA puts him just 79th among starting MLB pitchers). Lee (4-2, 2.86) has been very good. And Halladay -- well, you know how things have gone for Halladay.

Together, the top three pitchers on the team have combined for a 4.83 ERA and 7-12 record. Those numbers are obviously skewed by Halladay?s less-than-stellar/pre-surgery output. Even so, the numbers are the numbers. And when you measure those numbers against some other numbers (mainly the pitchers? combined $64.5 million price tag), none of the numbers look great.

Then there?s Howard. He went 0 for 4 against the Indians on Wednesday. He entered the day hitting .252/.291/.446 with six home runs and 22 RBIs. That?s not exactly $20 million man production. (Somewhere, Lee Majors is shaking his rebuilt robot head at the price of inflation.)

In fairness, they?re only four guys. Four out of 25 on the roster. But they?re also four of the highest paid professional athletes in the country -- as well as four of the most important Phillies. Sports Illustrated is right. They?re fortunate men. Wonder if the Phils feel the same way.

Source: http://www.csnphilly.com/baseball-philadelphia-phillies/has-money-been-well-spent-phillies

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Kabul car bomb kills 2 NATO troops, 4 contractors

KABUL, Afghanistan (AP) ? A suicide bomber rammed his car into a NATO convoy in the Afghan capital on Thursday, killing at least 12 people, including two coalition troops, four civilian contractors and two children, officials said.

A Muslim militant group, Hizb-e-Islami, claimed responsibility for the early morning attack and said it had targeted an American convoy.

NATO did not immediately release the nationalities of the killed troops and contractors. Six Afghan civilians, including children, were also killed in the explosion, Kabul provincial police spokesman Hashmad Stanakzi said.

Hizb-e-Islami said its newly formed special "martyrdom" unit had been stalking the convoy for weeks. The announcement could mean a steep escalation for the movement, based in northeastern Afghanistan, which has fought against the American-led coalition but is also a fierce rival of the Taliban.

Severed body parts littered the scene of the blast in eastern Kabul, and one coalition vehicle was reduced to a mangled pile of metal. The explosion, which wounded more than 35 others people, was powerful enough to rattle buildings on the other side of the city.

The suicide bomber struck about 8 a.m. with a car packed with explosives. "The explosion was very big. It set the nearby buildings on fire," Stanakzi said.

Kabul Deputy Police Chief Daud Amin said it was difficult to count the dead because the blast had shredded many of the victims.

"We saw two dead bodies of children on the ground," Amin said. "But the rest of the bodies were scattered in pieces around."

A spokesman for Hizb-e-Islami, Haroon Zarghoon, told The Associated Press that one of the movement's operatives carried out the attack on what he described as two vehicles of American advisers.

He claimed that most of the American advisers were killed and their vehicles destroyed.

Zarghoon says the militant group has formed a new cell to carry out suicide attacks on U.S. and other coalition troops.

"The cell had been monitoring the movement and timing of the American convoy for a week and implemented the plan Thursday morning," Zarghoon said.

He claimed the cell was established in response to alleged American efforts to keep permanent bases and troops in Afghanistan even after the full NATO withdrawal.

The U.S. has repeatedly said it wants no permanent bases in Afghanistan after most foreign troops withdraw by the end of 2014, but President Hamid Karzai raised eyebrows last week when he announced he had agreed to an American request to keep nine bases. A smaller American force is expected to remain in the country to assist Afghans in keeping security, but the exact configuration of their work has not yet been decided.

Hizb-e-Islami is headed by 65-year-old former warlord Gubuddin Hekmatyar, a former Afghan prime minister and one-time U.S. ally who is now listed as a terrorist by Washington. The militia has thousands of fighters and followers across the country's north and east.

Hekmatyar, who was heavily financed by the U.S. during the 1980s occupation of Afghanistan by the former Soviet Union, has been declared a terrorist and is being hunted by Afghan and NATO troops. U.S. bombs have targeted his military chief Kashmir Khan in Kunar province in northeastern Afghanistan on the border with Pakistan.

However, Hekmatyar's son-in-law has also held peace talks with both Karzai and also American officials. In a further sign of the complexities of the Afghan insurgency, Hizb-e-Islami is also a rival to the Taliban insurgency, even though both movements share the goal of driving out foreign troops and establishing a state that would follow a strict interpretation of Islamic law.

Hekmatyar and the Taliban supreme leader, Mullah Omar, in particular, are said to share personal animosity.

Thursday's attack was the second in eight months claimed by Hizb-e-Islami. In September, the militant group claimed responsibility when a female suicide car bomber killed least 12 people. At the time, Hizb-e-Islami said the attack was revenge for the film "Innocence of Muslims," which was made by an Egyptian-born American citizen and infuriated Muslims abroad for its negative depiction of the Prophet Muhammad.

___

Associated Press writer Kay Johnson contributed to this report from Kabul.

Source: http://news.yahoo.com/kabul-car-bomb-kills-2-nato-troops-4-104417652.html

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Returning genetic incidental findings without patient consent violates basic rights

Public release date: 16-May-2013
[ | E-mail | Share ]

Contact: Martha Coventry
coven002@umn.edu
612-625-2948
University of Minnesota

Upcoming paper in 'Science' pushes back against recent recommendations from the American College of Medical Genetics and Genomics

MINNEAPOLIS/ST. PAUL (05/15/2012)Informed consent is the backbone of patient care. Genetic testing has long required patient consent and patients have had a "right not to know" the results. However, as 21st century medicine now begins to use the tools of genome sequencing, an enormous debate has erupted over whether patients' rights will continue in an era of medical genomics.

Recent recommendations from the American College of Medical Genetics and Genomics (ACMG) suggest no. On March 22, the ACMG released recommendations stating that when clinical sequencing is undertaken for any medical reason, laboratories must examine 57 other specific genes to look for incidental findings. These findings must then be reported to the clinician and the patient. In an April 25 "clarification," ACMG said that failure to report these findings would be considered "unethical." The patient has no opportunity to opt-out of the testing of the 57 genes, except to decline all sequencing. The recommendations also apply to children.

In a paper to be published in 'Science 'May 16 online ahead of print, authors Susan M. Wolf, J.D. (University of Minnesota), George J. Annas, J.D., M.P.H. (Boston University), and Sherman Elias, M.D. (Northwestern University) push back against these recommendations, and offer compelling reasons why patient autonomy must remain firmly in place as science advances. Their article on Patient Autonomy and Incidental Findings in Clinical Genomics urges ACMG to reconsider their recommendations. This article is published with a reply by Amy McGuire, J.D., Ph.D. (Baylor College of Medicine) and colleagues.

Wolf, Annas, and Elias argue that, "The ACMG's 'minimum list [of 57 genes]' includes mutations in genes that patients have long been able to refuse testing for, including cancer risk mutations (such as BRCA1) and cardiovascular risk mutations." They point out that "There are many circumstances in which a patient may decline such testing and information, even if the results could open avenues for intervention. The patient may already be battling another disease, such as advanced cancer, or be late in life and see more burden than benefit in added genetic information. The patient may also fear that 'extra' results in their medical record will invite risk of discrimination."

ACMG says that applying these recommendations to children may help adult family members understand their own health risks. However, Wolf et al. point out that "this is exactly what past recommendations have rightly rejected, in limiting genetic testing and disclosure of genetic information to what is medically necessary during childhood." The authors cite long-standing policy discouraging childhood testing for adult-onset conditions. "Delaying testing and return of genetic information not medically useful in childhood allows the child to reach adulthood and then make a choice based on his or her own values."

The ACMG indicates that their list of genes to test without consent will grow. Their report says that laboratories may look for variants in other genes, "as deemed appropriate," and that ACMG will review the roster of 57 genes annually. Wolf et al. voice concern that "As the list expands, so will the scope of testing without consent." The authors urge the importance of patients' rights, especially in an era of genome sequencing when extensive genetic information can be generated on any patient.

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[ | E-mail | Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 16-May-2013
[ | E-mail | Share ]

Contact: Martha Coventry
coven002@umn.edu
612-625-2948
University of Minnesota

Upcoming paper in 'Science' pushes back against recent recommendations from the American College of Medical Genetics and Genomics

MINNEAPOLIS/ST. PAUL (05/15/2012)Informed consent is the backbone of patient care. Genetic testing has long required patient consent and patients have had a "right not to know" the results. However, as 21st century medicine now begins to use the tools of genome sequencing, an enormous debate has erupted over whether patients' rights will continue in an era of medical genomics.

Recent recommendations from the American College of Medical Genetics and Genomics (ACMG) suggest no. On March 22, the ACMG released recommendations stating that when clinical sequencing is undertaken for any medical reason, laboratories must examine 57 other specific genes to look for incidental findings. These findings must then be reported to the clinician and the patient. In an April 25 "clarification," ACMG said that failure to report these findings would be considered "unethical." The patient has no opportunity to opt-out of the testing of the 57 genes, except to decline all sequencing. The recommendations also apply to children.

In a paper to be published in 'Science 'May 16 online ahead of print, authors Susan M. Wolf, J.D. (University of Minnesota), George J. Annas, J.D., M.P.H. (Boston University), and Sherman Elias, M.D. (Northwestern University) push back against these recommendations, and offer compelling reasons why patient autonomy must remain firmly in place as science advances. Their article on Patient Autonomy and Incidental Findings in Clinical Genomics urges ACMG to reconsider their recommendations. This article is published with a reply by Amy McGuire, J.D., Ph.D. (Baylor College of Medicine) and colleagues.

Wolf, Annas, and Elias argue that, "The ACMG's 'minimum list [of 57 genes]' includes mutations in genes that patients have long been able to refuse testing for, including cancer risk mutations (such as BRCA1) and cardiovascular risk mutations." They point out that "There are many circumstances in which a patient may decline such testing and information, even if the results could open avenues for intervention. The patient may already be battling another disease, such as advanced cancer, or be late in life and see more burden than benefit in added genetic information. The patient may also fear that 'extra' results in their medical record will invite risk of discrimination."

ACMG says that applying these recommendations to children may help adult family members understand their own health risks. However, Wolf et al. point out that "this is exactly what past recommendations have rightly rejected, in limiting genetic testing and disclosure of genetic information to what is medically necessary during childhood." The authors cite long-standing policy discouraging childhood testing for adult-onset conditions. "Delaying testing and return of genetic information not medically useful in childhood allows the child to reach adulthood and then make a choice based on his or her own values."

The ACMG indicates that their list of genes to test without consent will grow. Their report says that laboratories may look for variants in other genes, "as deemed appropriate," and that ACMG will review the roster of 57 genes annually. Wolf et al. voice concern that "As the list expands, so will the scope of testing without consent." The authors urge the importance of patients' rights, especially in an era of genome sequencing when extensive genetic information can be generated on any patient.

###

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2013-05/uom-rgi051513.php

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Twitter Archiving Service TweetBackup Hits The Deadpool As Owner Backupify Focuses More On Enterprise

Time for a back-up plan for your Twitter back-up plan. Backupify -- the Cambridge, MA cloud-based backup, search and restore provider for online services -- is shutting down?TweetBackup, a company originally founded in Sweden that Backupify?acquired in 2010 for an undisclosed amount.?Tweetbackup has posted a note about the closure on its site, as well as -- yes -- on its Twitter account, noting that new signups are stopping as of today, and that existing users will have 30 days, until June 28, to keep logging into their accounts and back up their Twitter data elsewhere.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/PhVlKSzJZT0/

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PFT: Ex-Saints, Chargers RB Muncie dies at 60

Getty Images

Former NFL defensive end turned boxer Ray Edwards believes his new sport makes him less exposed to physical harm.

Yes, Edwards believes boxing is safer than football.

?Football is the only sport that is 100-percent injury prone,? Edwards tells Martin Rogers of Yahoo! Sports.? ?[In football], you don?t know what is coming, where you are going to get hit, how you are going to get hit.? You play for a long time, chances are you are going to tear your MCL or ACL. You can break your leg, snap your femur, break your arm, break your neck. . . .

?In boxing you know where the hits are coming from ? it is the guy stood in front of you.? In boxing you might break your hand or break your nose and if you get knocked out you can get a concussion.? But also, the referee is right there and you are more protected.? In football, you never know.? The game moves at such a pace that you might never see it coming.? You can get hit when you are completely defenseless.?

Edwards makes a point that isn?t as implausible as it seems.? In boxing, the participant has greater control over his circumstances.? He?ll absorb only the damage he can?t prevent, and he has no concerns about being hit deliberately or accidentally when he?s neither looking nor prepared.

Still, the point of boxing is to inflict enough injury upon the opponent?s brain to render him incapable of continuing.

?There is some faulty thinking there,? Dr. Anthony Alessi, a veteran ringside doctor in Connecticut, told Rogers.? ?In football, accidents and injuries are a byproduct of the game, but the main objective is to get the ball over the line and score points.

?In boxing, the object of the sport is to neurologically impair your opponent, to injure their brain in some way to stop them from performing.? It sounds graphic, but that is effectively what you are looking for ? a knockout.?

Of course, no injury will be inflicted if the other boxer simply pretends to sustain a knockout, diving to the ground when Edwards places a punch in the vicinity of the fighter?s jaw.

If the NFL were to call Edwards, he?d drop boxing faster than a guy taking a dive, and Edwards would return to football despite the risks.? After all, with those risks comes a reward far greater than anything he?ll earn by beating on a smattering of cream puffs and tomato cans at county fairs and tractor pulls.

Source: http://profootballtalk.nbcsports.com/2013/05/14/chuck-muncie-dies-at-60/related/

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Video: Is AIG a Better Company Today?

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Source: http://www.nbcnews.com/video/cnbc/51895150/

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